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C. elegans publications from TAIWAN

Welcome to the CECF Taiwan

The nematode worm Caenorhabditis elegans has become an important tool in the scientific world resulting in over 23,000 publications until now. Fully sequenced genome, 3-day life cycle and a considerable high amount of protein-coding genes (21,000) with high homology to humans making it an attractive model organism.

Our goal is to increase scientific awareness about this important model organism and our mission is to assist creating up new C. elegans labs in Taiwan and to offer non-profit services for existing worm-labs.

Using worm as a research tool is highly beneficial based on its low cost and its easiness to be adapted after several training courses. We wish to support investigators during their transition from single cell research to C. elegans based model organism research providing methodically assistance, sharing mutant strains and plasmids, training students and offering lectures about C. elegans based research.

Our mission is to provide knowledge to help researchers to design and conduct experiments without C. elegans experience. We assist in developing experiments to test various hypothesis in the nematode that have been otherwise investigated only in cell culture or other models.


Download a list of all worm PIs in Taiwan!


Selected 2016-2018 publications from the Taiwan C. elegans community:



Dr. Oliver Wagner

Cilia length and intraflagellar transport regulation by kinases PKG-1 and GCK-2 in C. elegans sensory neurons. Mol Cell Biol. 2018 Jan 29. doi: 10.1128/MCB.00612-17. [Epub ahead of print].

Cover MCB vol. 38, no.7 (2018)

Dr. Oliver Wagner

Uptake of TiO2 Nanoparticles into C. elegans Neurons Negatively Affects Axonal Growth and Worm Locomotion Behavior. ACS Appl Mater Interfaces. 2018 Feb 21. doi: 10.1021/acsami.7b18818. [Epub ahead of print]

Dr. John Wang

Non-Mendelian assortment of homologous autosomes of different sizes in males is the ancestral state in the Caenorhabditis lineage. Sci Rep. 2017 Oct 9;7(1):12819.

Dr. Han-Sheng Chuang

Analyzing the locomotory gaitprint of Caenorhabditis eleganson the basis of empirical mode decomposition. PLoS One. 2017 Jul 24;12(7):e0181469.

Dr. Chung-Min Liao

Toxicity-based toxicokinetic/toxicodynamic assessment of bioaccumulation and nanotoxicity of zerovalent iron nanoparticles in Caenorhabditis elegans. Int J Nanomedicine 2017 Jun 26;12:4607-4621.

Dr. Ben-Yang Liao

Recruitment of histone modifications to assist mRNA dosage maintenance after degeneration of cytosine DNA methylation during animal evolution. Genome Res. 2017 Sep;27(9):1513-1524.

Dr. Daniel Tsun-Yee Chiu / Dr. Sze-cheng John Lo

Impaired embryonic development in glucose-6-phosphate dehydrogenase-deficient Caenorhabditis elegans due to abnormal redox homeostasis induced activation of calcium-independent phospholipase and alteration of glycerophospholipid metabolism. Cell Death Dis. 2017 Jan 12;8(1):e2545.

Dr. Chun-Liang Pan

A Wnt-planar polarity pathway instructs neurite branching by restricting F-actin assembly through endosomal signaling. PLoS Genet. 2017 Apr 6;13(4):e1006720.

Dr. Ben-Yang Liao

modPhEA: model organism Phenotype Enrichment Analysis of eukaryotic gene sets. Bioinformatics. 2017 Nov 1;33(21):3505-3507.

Dr. Vivian Hsiu-Chuan Liao

N-γ-(L-Glutamyl)-L-selenomethionine enhances stress resistance and ameliorates aging indicators via the selenoprotein TRXR-1 in Caenorhabditis elegans. Mol Nutr Food Res. 2017 Aug;61(8).

Dr. Yen-Ping Hsueh


Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey. Elife. 2017 Jan 18;6.

Dr. Vivian Hsiu-Chuan Liao

Chronic ZnO-NPs exposure at environmentally relevant concentrations results in metabolic and locomotive toxicities in Caenorhabditis elegans. Environ Pollut. 2017 Jan;220(Pt B):1456-1464.

Dr. Chang-Shi Chen

A Disease Model of Muscle Necrosis Caused by Aeromonas dhakensis Infection in Caenorhabditis elegans. Front Microbiol. 2017 Jan 4;7:2058.

Dr. Chang-Shi Chen

HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin in C. elegans. Autophagy. 2017 Feb;13(2):371-385.

Dr. Sze-cheng John Lo

Expression of hepatitis B virus surface antigens induces defective gonad phenotypes in Caenorhabditis elegans. World J Virol. 2017 Feb 12;6(1):17-25.

Dr. Yi-Chun Wu / Dr. Hung-Yuan (Pater) Chi

Functional characterization of the meiosis-specific DNA double-strand break inducing factor SPO-11 from C. elegans. Sci Rep. 2017 May 24;7(1):2370.

Dr. Daniel Tsun-Yee Chiu

What has passed is prolog: new cellular and physiological roles of G6PD. Free Radic Res. 2016 Oct 19:1-18.

Dr. Chun-Liang Pan

A C. elegans Thermosensory Circuit Regulates Longevity through crh-1/CREB-Dependent flp-6 Neuropeptide Signaling. Dev Cell. 2016 Oct 24;39(2):209-223.

Dr. Vivian Hsiu-Chuan Liao

Transgenerational Reproductive Effects of Arsenite Are Associated with H3K4 Dimethylation and SPR-5 Downregulation in Caenorhabditis elegans. Environ Sci Technol. 2016 Oct 4;50(19):10673-10681.

Dr. Chang-Shi Chen

Mutation of the Enterohemorrhagic Escherichia coli Core LPS Biosynthesis Enzyme RfaD Confers Hypersusceptibility to Host Intestinal Innate Immunity In vivo. Front Cell Infect Microbiol. 2016 Aug 12;6:82.

Dr. Vivian Hsiu-Chuan Liao

Monascin from Monascus-Fermented Products Reduces Oxidative Stress and Amyloid-β Toxicity via DAF-16/FOXO in Caenorhabditis elegans. J Agric Food Chem. 2016 Sep 28;64(38):7114-20.

Dr. Ta-Chau Chang / Dr. Sze-cheng John Lo

Specific polyunsaturated fatty acids modulate lipid delivery and oocyte development in C. elegans revealed by molecular-selective label-free imaging. Sci Rep. 2016 Aug 18;6:32021.

Dr. Yi-Chun Wu

Programmed Cell Death During Caenorhabditis elegans Development. Genetics. 2016 Aug;203(4):1533-62.

Dr. Yuan, Hanna

Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G. Cell Rep. 2016 Jul 12;16(2):279-87

Dr. Yuan, Hanna

Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization. Science. 2016 Jul 22;353(6297):394-9.

Dr. Chang-Shi Chen

Exercise in an electrotactic flow chamber ameliorates age-related degeneration in Caenorhabditis elegans. Sci Rep. 2016 Jun 16;6:28064

Dr. Chein-Chia Wang

A WHEP Domain Regulates the Dynamic Structure and Activity ofCaenorhabditis elegans Glycyl-tRNA Synthetase. J Biol Chem. 2016 Aug 5;291(32):16567-75.

Dr. Chung-Min Liao

In situ remediation-released zero-valent iron nanoparticles impair soil ecosystems health: A C. elegans biomarker-based risk assessment. J Hazard Mater. 2016 Nov 5;317:210-20.

Dr. Vivian Hsiu-Chuan Liao

Antioxidative Activities of Both Oleic Acid and Camellia tenuifolia Seed Oil Are Regulated by the Transcription Factor DAF-16/FOXO in Caenorhabditis elegans. PLoS One. 2016 Jun 8;11(6):e0157195.

Dr. Oliver Wagner

Identification and Characterization of LIN-2(CASK) as a Regulator of Kinesin-3 UNC-104(KIF1A) Motility and Clustering in Neurons. Traffic. 2016 Aug;17(8):891-907.

Dr. Sze-cheng John Lo

Genetic control of nucleolar size: An evolutionary perspective. Nucleus. 2016 Apr 25;7(2):112-20.

Dr. Vivian Hsiu-Chuan Liao

Nanoscale zerovalent iron (nZVI) at environmentally relevant concentrations induced multigenerational reproductive toxicity in Caenorhabditis elegans. Chemosphere. 2016 May;150:615-23

Dr. Vivian Hsiu-Chuan Liao

Arsenite exposure accelerates aging process regulated by the transcription factor DAF-16/FOXO in Caenorhabditis elegans. Chemosphere. 2016 May;150:632-8

Dr. Shih-Peng Chan

A novel function for the DEAD-box RNA helicase DDX-23 in primary microRNA processing in Caenorhabditis elegans. Dev Biol. 2016 Jan 15;409(2):459-72.

Dr. Hao-Chieh Chiu

In vitro and in vivo activity of a novel sorafenib derivative SC5005 against MRSA. J Antimicrob Chemother. 2016 Feb;71(2):449-59.

Dr. Yi-Chun Wu / Dr. Chao-Ping Hsu

Noise propagation with interlinked feed-forward pathways. Sci Rep. 2016 Mar 31;6:23607.

Dr. Chang-Shi Chen

HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin in C. elegans. Autophagy. 2016 Nov 22:0. [Epub ahead of print]

The CECF consists of three cores, the north core at NTU, the center core at NTHU and the south core at NCKU:

Thanks for visiting us and we hope serving you soon!